Evan Bartlett is a member of the business development team at Angelsoft. Lifeinlists is his digital sandbox and he recently published his Top 10 most useful webapps of 2008 there. On the list: Highrise.
Highrise
Highrise became a big-small contender in the CRM space this year by adding Deal tracking and full data export. Not to mention, no CRM comes close to making it this easy to keep track of your contacts in detail. After falling off the wagon with Salesforce (multiple times), SugarCRM, and PipelineDeals, Highrise is the only one that became critical to my day-to-day activites at work.
Thanks for the mention Evan.